Clinical Psychopharmacology and Neuroscience Papers in Press available online.

Effects of Psychosocial Interventions for Patients with Breast Cancer: A Meta-Analysis
Kyu-Sic Hwang 1,2, Seung-Ho Jang 1,2,3, Chan-Mo Yang 1,2,3, Hye-Jin Lee 4, Sang-Yeol Lee 1,2,3,*
1Department of Psychiatry, Wonkwang University Hospital, 2Korea Brain-Behavior Mental Health Institute, 3Department of Psychiatry, School of Medicine, Wonkwang University, 4Department of Public Health, Wonkwang University Graduate School
Objective: This study involved a meta-analysis of South Korean studies regarding psychosocial interventions for patients with breast cancer to provide basic data to support the development of an integrated healthcare service model.
Methods: Randomized controlled studies with a pretest-posttest design were selected, and those presenting means, standard deviations, and standardized mean differences were included. For quality evaluation and heterogeneity testing, the Jadad scale and the Q-value and I2 were used. To estimate the effect size of each study, Hedge’s g was used. Publication bias was analyzed with the Funnel plot and Egger’s regression test.
Results: Of the 28 studies selected for the, meta-analysis was performed on eight. The total number of datasets included in the meta-analysis was 33. The evaluation based on the Jadad scale revealed no significant inter-rater variation (p = 0.35). The mean number of sessions was 7.93 and the mean intervention time was 13.2 hours. The interventions were mostly administered in a group structure (94%) and, regarding the type, they were categorized as integrated (36.4%), cognitive (30.3%), and meditation (24.2%). The mean effect size was 1.21 against no treatment group.
Conclusion: The analyzed studies showed heterogeneity, with a corresponding asymmetry found on the funnel plot. Despite the heterogeneity and publication bias, the mean effect size was significantly large. Cognitive interventions, meditation, and psychological education programs are expected to assist in reducing negative emotions and enhancing quality of life in patients with breast cancer.
Accepted Manuscript [Submitted on 2021-08-09, Accepted on 2021-10-20]