Clinical Psychopharmacology and Neuroscience Papers in Press available online.

 
Aripiprazole Improved Post-Streptococcal Dyskinesia by Modulating Dopaminergic Activity: A Case Report
Jae Hyun Ryou 1, Doug Hyun Han 1, Reeree Lee 2, Sun Mi Kim 1,*
1Department of Psychiatry, College of Medicine, Chung-Ang University, Seoul, Korea, 2Department of Nuclear Medicine, Chung-Ang University Hospital, Seoul, Korea
Abstract
This case report aimed to discuss the efficacy of aripiprazole for dyskinesia in patients with functional movement disorder after streptococcal infection, with its biological action of modulating dopamine hyperactivity in the basal ganglia as a dopamine partial agonist. This report has shown that the [18F] N‐(3‐Fluoropropyl)‐2β‐carbon ethoxy‐3β‐(4‐iodophenyl) nortropane (FP‐CIT) positron emission tomography findings of the patient revealed that the dopamine hyperactivity in the basal ganglia at baseline was normalized after aripiprazole treatment due to its balancing effect as a dopamine partial agonist.
Accepted Manuscript [Submitted on 2021-06-21, Accepted on 2021-10-06]