Psychosomatics: Communication of the Central Nervous System through Connection to Tissues, Organs, and Cells
Andrei Efremov
Mind Networks Association LLC, Wilmington, NC, USA
Correspondence to: Andrei Efremov
Mind Networks Association LLC, 500 Delaware Ave., Wilmington, NC 19899, USA
E-mail: andrei_efremov@outlook.com
ORCID: https://orcid.org/0009-0009-0607-4549
Received: April 18, 2024; Revised: July 16, 2024; Accepted: August 8, 2024; Published online: September 6, 2024.
© The Korean College of Neuropsychopharmacology. All rights reserved.

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
This study aimed to scrutinize existing evidence concerning the link between somatic symptoms and nervous system activity. The goal was to pinpoint areas for effective therapeutic interventions. Psychosomatic disorders, an often overlooked field of medicine, bears significance given the multitude of patients experiencing somatic symptoms due to specific emotions and experiences. The literature was explored using the methods of comparative analysis, synthesis and graphical representation. The study introduced pathological neural networks localized in brain regions such as the prefrontal cortex and hippocampus, leading to maladaptive behaviors and heightened negative focus. Activation of the sympathetic nervous system and the hypothalamus-pituitary-adrenal axis, alongside increased cortisol levels, induces chronic distress, inflammation, and disruptions in neurotransmitter metabolism. The gut microbiota significantly influences psychosomatic reactions. Patients with psychosomatic disorders require complex treatment with cognitive-behavioural therapy and hypnosis methods. Within the framework of pathological neural networks, the MindChat technique has yielded effectiveness with the purpose of “dehypnotization” and destruction of aberrant cognitive and emotional patterns. However, it should be noted that this technique requires further empirical support.
Keywords: Psychosomatic medicine; Cell communication; Neuroimmunomodulation; Organ specificity; Signal transduction

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