Fig. 4. Peripheral blood and tissue 5-HT of mice and rats. (A) Serum 5-HT of mice at the end of CUMS. (B) Plasma 5-HT of mice at the end of CUMS. (C) Platelet 5-HT of mice at the end of CUMS (n = 10 in NC group, n = 20 in CUMS group). (D) Serum 5-HT of mice after treatment. (E) Plasma 5-HT of mice after treatment. (F) Platelet 5-HT of mice after treatment (n = 10/group). (G) Cerebral cortex 5-HT of mice. (H) Hippocampus 5-HT of mice. (I) Colon 5-HT of mice. (J) Serum 5-HT of rats at the end of CUMS. (K) Plasma 5-HT of rats at the end of CUMS. (L) Platelet 5-HT of rats at the end of CUMS (n = 10 in NC group, n = 20 in CUMS group). (M) Serum 5-HT of rats after treatment. (N) Plasma 5-HT of rats after treatment. (O) Platelet 5-HT of rats after treatment (n = 10/group). (P) Cerebral cortex 5-HT of rats. (Q) Hippocampus 5-HT of rats. (R) Colon 5-HT of rats. Data were shown as the mean ± standard error of mean. Statistical com-parisons between the two groups were performed using the two independent samples t test. Com-parisons between multiple groups were performed using one-way analyses of variance and Tukey test.
5-HT, 5-hydroxytryptamine; NC, nor-mal control; CUMS, chronic unpredictable mild stress; FLX, fluoxetine.
*p < 0.05, **p < 0.01.
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