Fig. 1. Incidence rate ratio (IRR) and 95% confidence intervals (95% CIs) from the per protocol analysis. Presented are the main effects for time and group allocation and the time by group interaction were tested for each outcome using log-linked, generalised linear models for Poisson distributed dichotomous outcomes. The statistically significant themes are displayed; depressive affect improved (A), depressive affect positive (B), functioning good (C), optimism (D), relationship bad (E), functioning improved (F), over the course of the 12 weeks of treatment and 4 weeks after discontinuation. NAC, N-acetylcysteine.
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