Various psychiatric manifestation in DiGeorge syndrome(22q11.2 deletion syndrome): a case report
Giok Kim 1, Eunsoo Moon 1, 2*, Je Min Park 1, 2, Byung Dae Lee 1, 2, Young Min Lee 1, 2, Hee Jeong Jeong 1, Soo yeon Kim 1, Kang yoon Lee 1, Hwagyu Suh 1
1Department of Psychiatry, Medical Research Institute, Pusan National University Hospital, Busan, Republic of Korea, 2Department of Psychiatry, Pusan National University School of Medicine, Yangsan, Republic of Korea
Received: February 14, 2019; Revised: March 18, 2019; Accepted: March 18, 2019; Published online: March 18, 2019.
© The Korean College of Neuropsychopharmacology. All rights reserved.

This case report aimed to describe various psychiatric manifestation and treatment course in a patient with DiGeorge syndrome. Psychiatric symptoms and treatment course in a female patient with DiGeorge syndrome were described. This patient showed psychotic symptoms, mood symptoms, and intellectual disability. As well as various psychiatric symptoms, treatment response and sensitivity of side effect by antipsychotics were different from typical characteristics in psychiatric disorders. This case suggests that the genetic defect in DiGeorge syndrome might have a great association with psychiatric problems and response of antipsychotics.
Keywords: 22q11.2 deletion syndrome, DiGeorge syndrome, CATCH22 syndrome, psychosis, mood, intellectual disability, seizure, antipsychotics