The influence of current mood states on screening accuracy of the Mood Disorder Questionnaire
Hee Ryung Wang 1, Won-Myong Bahk 2*, Bo-Hyun Yoon 3, Moon-Doo Kim 4, Young-Eun Jung 4, Kyung Joon Min 5, Jeongwan Hong 6, Young Sup Woo 2
1Yeongdeungpo Community Health Center, Seoul, Korea, 2Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea, 3Department of Psychiatry, Naju National Hospital, Naju, Korea, 4Department of Psychiatry, Jeju National University Hospital, Jeju, Korea, 5Department of Psychiatry, Chung-Ang University, Seoul, Korea, 6Department of Psychiatry, Iksan Hospital, Iksan, Korea
Received: August 31, 2018; Revised: November 1, 2018; Accepted: November 14, 2018; Published online: November 14, 2018.
© The Korean College of Neuropsychopharmacology. All rights reserved.

Aim: In this study we investigated whether current mood states of patients with bipolar disorder have an influence on the screening accuracy of the Mood Disorder Questionnaire (MDQ).
Methods: A total of 452 patients with mood disorder (including major depressive disorder (MDD, n=192) and bipolar disorder (n=260)) completed the Korean version of the MDQ. Patients with bipolar disorder were subdivided into three groups (bipolar depressed only, bipolar euthymic only, bipolar manic/hypomanic only) according to current mood states. The screening accuracy of the MDQ including sensitivity, specificity and area under the curve (AUC) of receiver operating characteristic (ROC) curves were evaluated according to current mood states.
Results: The optimal cutoff of MDQ was 5 in this study sample. Sensitivity and specificity were not significantly different according to current mood states. Significant differences in AUCs of four independent ROC curves were not found (ROC 1st curve included all bipolar patients; ROC 2nd curve included only bipolar depressed patients; ROC 3rd curve included only bipolar manic/hypomanic patients; ROC 4th curve included only bipolar euthymic patients).
Conclusion: The study results showed that current mood states (either euthymic state, depressed or manic/hypomanic) did not significantly influence the screening accuracy of the MDQ suggesting that the MDQ could be a useful screening instrument for detecting bipolar disorder in clinical practice regardless of the current mood symptoms of subjects.
Keywords: Mood disorder questionnaire, current mood states, sensitivity, specificity, area under the curve