Chronic blockade of the purinergic 2X7 receptor produces antidepressant-like effects through inhibition of NLRP1 inflammasome in chronic unpredictable mild stress model of depression in rats
Feyza Aricioglu 1, Ceren Sahin Ozkartal 1, Tugce Bastaskin 1, Erdem Tuzun 2*, Cansu Kandemir 3, Serap Sirvanci 3, Cem İsmail Küçükali 2, Tijen Utkan 4
1Marmara University School of Pharmacy, Department of Pharmacology and Psychopharmacology Research Unit, Istanbul, Turkey, 2Istanbul University Aziz Sancar Institute of Experimental Medical Research, Neuroscience Department, Istanbul, Turkey, 3Marmara University School of Medicine, Department of Histology and Embryology, Istanbul, Turkey, 4Kocaeli University School of Medicine, Department of Pharmacology, Kocaeli, Turkey