NEW ONSET OBSESSIVE COMPULSIVE DISORDER FOLLOWING HIGH FREQUENCY REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION OVER LEFT DORSOLATERAL PREFRONTAL CORTEX FOR TREATMENT OF NEGATIVE SYMPTOMS IN A PATIENT WITH SCHIZOPHRENIA
Harshit Garg , Saurabh Kumar , Swarndeep Singh , Nand Kumar , Rohit Verma *
All India Institute of Medical Sciences, Delhi, India
Received: January 28, 2018; Revised: February 23, 2018; Accepted: March 4, 2018; Published online: March 4, 2018.
© The Korean College of Neuropsychopharmacology. All rights reserved.

Abstract
Obsessive-compulsive symptoms and/or obsessive-compulsive disorders (OCD) are frequently comorbid with schizophrenia, though the exact clinical and etiological relationship between them is poorly understood. Here we describe a case that, to the best of our knowledge, is the first report of new-onset OCD in a patient who was receiving high-frequency repetitive transcranial magnetic stimulation over left dorsolateral pre-frontal cortex as an adjuvant therapy for negative symptoms of schizophrenia. This report supports our understanding of OCD as a brain disorder involving hyperactivity of pre-frontal cortex and cortico-striatal-thalamo-cortical circuit dysfunction.
Keywords: OCD, Negative symptoms, Schizophrenia, rTMS


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