Cognitive deficits in schizophrenia: Understanding the biological correlates and remediation strategies
ADARSH TRIPATHI , SUJITA KUMAR KAR *, RASHMI SHUKLA
KING GEORGE’S MEDICAL UNIVERSITY, LUCKNOW, U.P, INDIA
Received: February 14, 2017; Revised: June 22, 2017; Accepted: July 16, 2017; Published online: July 16, 2017.
© The Korean College of Neuropsychopharmacology. All rights reserved.

Abstract
Cognitive deficits are one of the core symptoms of schizophrenia that evolve during the course of schizophrenia, after being originated even before the onset of illness. Existing pharmacological and biological treatment modalities fall short to meet the needs to improve the cognitive symptoms; hence various cognitive remediation strategies have been adopted to address these deficits. Research evidences suggest that cognitive remediation measures improve the functioning, limit disability bettering the quality of life. The functional outcomes of cognitive remediation in schizophrenia are resultant of neurobiological changes in specific brain areas. Recent years witnessed significant innovations in cognitive remediation strategies in schizophrenia. This comprehensive review highlights the biological correlates of cognitive deficits in schizophrenia and the remedial measures with evidence base.
Keywords: Cognitive deficits, Schizophrenia, Cognitive Remediation, Neurobiology


e-submission

Archives