Psychometric properties of the Hypomania Checklist-32 (KHCL-32-R2) in Korean patients with mood disorders
Bo-Hyun Yoon 1, Won-Myong Bahk 3*
1Department of Psychiatry, Naju National Hospital, Naju, 22Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland, 3Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, 4Hangang Mental Clinic, Gimpo, 5Department of Psychiatry, Jeju National University Hospital, Jeju, 6Department of Psychiatry, Chung-Ang University, Seoul, 7Department of Psychiatry, National Center for Mental Health, Seoul, 8Department of Psychiatry, Kyungpook National University School of Medicine, Daegu, 9Department of Psychiatry, Iksan Hospital, Iksan
Received: January 10, 2017; Revised: February 16, 2017; Accepted: February 16, 2017; Published online: February 16, 2017.
© The Korean College of Neuropsychopharmacology. All rights reserved.

Objective: The aim of this study was to examine the validity of the Korean version of the HCL-32-R2 (KHCL-32-R2) in mood disorder patients.
Methods: A total of 454 SCID-CV diagnosed mood disorder patients (bipolar I (BD-I), n=190; bipolar II (BD-II), n=72; and major depressive disorder (MDD), n=192) completed the Korean module of the HCL-32-R2.
Results: The KHCL-32-R2 showed a three-factorial structure (eigenvalue > 2) that accounted for 43.26% of the total variance. Factor 1 was labeled “active/elated” and included 16 items; factor 2, “irritable/distractible” and included 9 items; and factor 3 was labeled “risk-taking/indulging” and included 9 items. A score of 16 or more on the KHCL-32-R2 total scale score distinguished between BD and MDD, which yielded a sensitivity of 70% and a specificity of 70%. MDD and BD-II also could be differentiated at a cut-off of 15 with maximized sensitivity (0.67) and specificity (0.66). Cronbach’s alpha of KHCL-32-R2 and its subsets (factors 1, 2, and 3) were 0.91, 0.89, 0.81 and 0.79, respectively. Correlations between KHCL-32-R2 and MADRS, YMRS and K-MDQ were -0.66 (p=0.41), -0.14 (p=0.9), and 0.61 (p<0.001), respectively.
Conclusion: The KHCL-32-R2 may be a useful tool in distinguishing between bipolar and depressive patients in clinical settings.
Keywords: HCL-32-R2, Validation, Sensitivity, Specificity, Bipolar disorder, Major depression