Donepezil for compulsive behavior in Degenerative dementia: Case series
Biswa Ranjan Mishra 1, Venteemar S SREERAJ 2*, Saranya Dhanashekarana 2, Rituparna Maiti
1Department of Psychiatry, All India Institute of medical Sciences, Bhuvaneshwar, India, 2Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India, 3Department of Pharmacology, All India Institute of medical Sciences, Bhuvaneshwar, India.
Received: October 21, 2016; Revised: January 19, 2017; Accepted: January 20, 2017; Published online: January 20, 2017.
© The Korean College of Neuropsychopharmacology. All rights reserved.

Abstract
Diagnosing and managing dementia, presenting with compulsions is challenging. Presented are three cases, a possible representative subset of the Donepezil responders. Selective degeneration of dorsolateral prefrontal cortex networking striatum leading to compulsions would be amenable to cholinergic modulation.
Keywords: Compulsions, Psychosis, Fronto-temporal dementia, Major Neurocognitive disorder, Donepezil


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