Successful Treatment with Olanzapine of Psychosis in Dentatorubral-pallidoluysian atrophy: A Case Report
Zui Narita 1*, Tomiki Sumiyoshi 1
National Center of Neurology and Psychiatry
Received: October 18, 2016; Revised: December 6, 2016; Accepted: December 8, 2016; Published online: December 8, 2016.
© The Korean College of Neuropsychopharmacology. All rights reserved.

Patients with dentatorubral-pallidoluysian atrophy occasionally elicit psychosis. So far, one study reported first generation antipsychotics drugs may provide an effective treatment;1) however, there is no literature on the benefits of second generation antipsychotics. We report on a 44-year-old man found to have psychotic disorder due to dentatorubral-pallidoluysian atrophy whose psychosis was effectively treated with olanzapine. Our observation indicates some second generation antipsychotics provide a therapeutic option for ameliorating psychosis in dentatorubral-pallidoluysian atrophy.
Keywords: Dentatorubral-pallidoluysian atrophy, Spinocerebellar degeneration disease, Psychosis, Second generation antipsychotics, Olanzapine